Lipido PEG Linkers, also referred to as PEGylated lipids, have become a popular focus in drug delivery. These amphiphilic molecules feature a hydrophilic polyethylene glycol (PEG) component linked to a hydrophobic lipid tail, which produces a distinct structure that can dissolve in both water and lipids. This quality makes it an appealing alternative for enhancing the stability, pharmacokinetics, and bioavailability of various therapeutics, including small molecules, proteins, and peptides. PEG Lipids have two main properties that contribute to their potential as a drug delivery system: biocompatibility and the ability to self-assemble into stable structures such as liposomes or micelles.