ɑ,ω-Bis-Maleimido PEGs

Linear bifunctional PEG maleimide reagents are crosslinking reagents for thiol substrates. The maleimide group reacts at about neutral pH with free thiols via a Michael addition to form a stable thioether bond. This PEG derivative has also been used in Diels Alder type click reactions to crosslink diene substrates.


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