€ 1.570,00*
RAI1202.1G
Product information
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. The graft copolymer shows modified physicochemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix) and has hydrophobic and hydrophilic properties. These copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions.The PEG spacer is in the range of MW 3000 Da. TentaGel® resins have high diffusion rates and excellent swelling in a wide range of solvents from e.g. toluene to water.
TentaGel® R TRT Resins preloaded with heavy isotopes amino acids (13C, 15N). Peptides containing heavy labeled AA make them ideal for MS analysis and quantfication of complex peptide and protein mixtures.
Literature
L 108 Resins with Isotope Labeled Amino Acids
- Nauwelaerts, S. J. D.; Roosens, N. H. C.; Bernard, A.; De Keersmaecker, S. C. J.; De Cremer, K. Development of a multiplex mass spectrometry method for simultaneous quantification of urinary proteins related to respiratory health. Scientific Reports, 2021,11(1). doi:10.1038/s41598-021-89068-9
- Wiśniewski, J. R.; Wegler, C.; Artursson, P. Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking. J. Proteome Res. 2019, 18, 217−224. doi: 10.1021/acs.jproteome.8b00549