Hydroxytrityl HypoGel® Resins (TRT Linker)
HypoGel® is a hydrophilic
gel
type resin which combines high loading and a hydrophilicity between polystyrene and TentaGel®. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone.
Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM.
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